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Higher (10 g/kg) dosage was effective either after a single or daily regimen, whereas lower (10 ng/kg) dosage, previously ineffective given as a single application, becomes efficacious when applied as a daily regimen

[150] reported that transferrin-conjugated CDs co-loaded with temozolomide and epirubicin produced markedly enhanced cytotoxicity across multiple GBM cell lines compared to single-drug formulations, illustrating the advantage of combined targeting and multi-drug delivery strategies [150]

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