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thus, more objective evidence is needed to support their conclusions

Among them, preobesity/obesity, MASLD and some coexisting hypertension, closely related to poor lifestyle, are independent risk factors for the development of cardiovascular-kidney-metabolic syndrome and T2D, 2 indicating their preventable characteristic

Our research shows that the supplementation of melatonin can restore the expression of core glycolytic genes through metabolic reprogramming of glucose metabolism in porcine granulosa cells and mouse ovaries, respectively, thereby improving lactate production, further enhancing lactylation, and inhibiting ferroptosis

Importantly, the withdrawal of AFB1 restored the observed changes in rat brain (242)