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Expectations may be unrealistic

Polymannuronic acid ameliorated obesity and inflammation associated with a high-fat and high-sucrose diet by modulating the gut microbiome in a murine model

The fetal liver exhibited higher mitochondrial activity and increased mitochondrial DNA copy numbersboth indicative of enhanced energy metabolismwithout major shifts in gene expression, suggesting that regulation may occur at the protein level (Safain et al., 2025)

35,52 Extrinsic signals from fibro-adipogenic progenitors and macrophages also modulate MuSC activation, proliferation, and differentiation during both regeneration and aging