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It can also decrease the cellular action of circulating thyroid hormones, potentially interfering with medications like Levothyroxine used for hypothyroidism, which could paradoxically worsen fatigue if unmonitored

doi: 10.1016/j.rbmo.2011.03.015

Liver disease The liver is the primary site of lipid synthesis and metabolism, and thus, hepatic disorders are frequently associated with lipid metabolic dysregulation