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In addition, levels of RNA oxidation in CSF were higher in subjects with shorter duration of AD (59), as well as with higher cognitive scores

Using Seahorse extracellular flux analyses, the present study found that SR4 significantly enhanced mitochondrial respiration, increasing OCR across multiple respiratory states including basal (state 2), ADP-stimulated (state 3), uncoupled maximal respiration (state 3u), proton leak and SRC