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Acidic environments cause histidine peptides to become protonated, which damages cancer cells via permeability of membrane 121

If youre going to reach for an energy or coffee drink, I recommend drinking one that is low in calories and uses an artificial sweetener like sucralose, that has been well researched and is generally regarded as safe

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In doxorubicin-resistant human uterine sarcoma (MES-SA/Dx5), apigenin reduces intracellular glutathione (GSH) levels by inhibiting ATP-binding cassette subfamily B member 1 (ABCB1) [60], while in prostate cancer, it reverses doxorubicin resistance by down-regulating ABCB1 protein expression [61]