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Clinical research has primarily employed intravenous infusions at high doses, though subcutaneous administration at lower doses is emerging as a practical maintenance route [2] [3]

3-Year follow-up of temporary implantable nitinol device implantation for the treatment of benign prostatic obstruction

Note on visceral (smooth-muscle) cramps: Cramping sensations in the abdomen or chest (e.g., oesophageal spasm) or gut are typically due to visceral smooth-muscle activity or underlying organ pathology (e.g., colic, biliary colic, bowel obstruction, oesophageal spasm) and should be evaluated differently from skeletal muscle cramps

However, people with low B12 can also experience mental fatigue