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249 In patients with TNBC who have received neoadjuvant chemotherapy, researchers utilized scRNA-seq to identify that chemotherapy can induce the accumulation of ICOSL+ B cells

N-acetyl cysteine overdose induced acute toxicity and hepatic microvesicular steatosis by disrupting gsh and interfering lipid metabolisms in normal mice

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These effects have been particularly relevant in neurodegenerative conditions and metabolic disorders, where mitochondrial dysfunction plays a central role