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Chemical Biology & Drug Design, 81(1), 136-147

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Multiple factors contribute to the development of IBS after COVID infection: Active viral replication within gut epithelial cells, demonstrated by recent research Altered microbiota composition affecting serotonin pathways Increased intestinal permeability following infection Psychological factors including anxiety and depression This article examines the current understanding of treatment for post COVID IBS based on recent evidence from ongoing research initiatives such as the Arizona CoVHORT study tracking over 9,000 participants