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For intracellular staining of phospho(p)-mTOR (Fisher Scientific 15549836) and p-S6 (eBioscience 15528216), cells were first stained for extracellular markers, fixed in 2% FA at RT, and stained for p-mTOR and p-S6 diluted 1:200 in saponin 5 g/mL

miR-206 participates in the regulation of gene expression by targeting Notch3 and vascular endothelial growth factor A (VEGFA) mRNA 3-UTR after prediction by the bioinformatics gene database