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Once the bilayer membrane has been stretched, it begins to close the loop at a slow rate, forming mitochondrial autophagosomes

Morphologically, necroptosis typically presents as cellular swelling, whereas ferroptosis is characterized by reduced mitochondrial volume and decreased cristae [120]

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5 Gut microbiota and metabolites targeted interventions against CKD progression in the gut-brain-kidney axis Gut dysbiosis is implicated in the progression of a range of diseases, including cardiovascular disease, type 2 diabetes, neurodegenerative conditions, and CKD, among others, via mechanisms that are yet to be completely understood