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Proline modulates the intracellular redox environment and protects mammalian cells against oxidative stress

Even if cysteine S -conjugate -lyase is responsible for the synthesis of the highly reactive and cytotoxic thiol version of cisplatin ( Figure 1 ), the activation of cisplatin into a nephrotoxin relies on the three previous steps of the classical mercapturic acid pathway involving GSTs (GSH conjugation), GT (production of CisPt-cys-glu) and dipeptidase (production of CisPt-cys

Corn silk ( Zea mays L.) induced apoptosis in human breast cancer (MCF-7) cells via the ROS-mediated mitochondrial pathway

Advanced ovarian cancer is often accompanied by ascites, excessive fluid accumulation in the abdominal cavity 23 , and routine medical care involves ascites drainage