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Other common causes of vitamin B12 deficiency include gastrectomy, ileal resection, pancreatic insufficiency and malabsorption syndromes including Crohns disease and coeliac disease. The bottom line : for patients with the above gastrointestinal challenges, getting enough B12 into the bloodstream through oral supplementation is not possible

In vitro characterization of the anticancer activity of membrane-active cationic peptides

McIver SC, Stanger SJ, Santarelli DM, Roman SD, Nixon B, McLaughlin EA

Resources covering whether 50 units is a lot or 20 units is too much provide context for evaluating your dosing relative to standard protocols