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[] DNA methylation DNA methylation typically leads to transcriptional repression by promoting a condensed chromatin structure through covalent attachment of a methyl group to the 5 carbon of cytosine bases, predominantly within cytosine-phosphate-guanine dinucleotide site (CpG) dinucleotides

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Intralesional administration.When the strength and dosage form of the drug lend the preparation to the treatment of the condition, those products labeled for intralesional administration are indicated for: Keloids Localized hypertrophic, infiltrated, inflammatory lesions of: lichen planus, psoriatic plaques, granuloma annulare, and lichen simplex chronicus (neurodermatitis) Discoid lupus erythematosus Necrobiosis lipoidica diabeticorum Alopecia areata They also may be useful in cystic tumors of an aponeurosis tendon (ganglia)