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doi: 10.1016/S1474-4422(23)00375-7 97 KochenderferJNDudleyMEFeldmanSAWilsonWHSpanerDEMaricIet al

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These findings highlight glutamines capacity to reinforce antioxidant enzyme activity within HDL and demonstrate that exercise further augments PON-1 responsiveness, a key mechanism for vascular protection in older adults ( Across these clinical trials, a coherent pattern emerges: glutamine supplementation provides measurable benefits for redox regulation and inflammatory balance in aging populations, with the most pronounced effects occurring when combined with structured exercise