glutathione increase after treating with platinum drugs

glutathione increase after treating with platinum drugs Role of in Cancer: From Mechanisms to Therapies Glutathione peroxidase 4‐dependent glutathione high‐consumption

Name: glutathione increase after treating with platinum drugs Role of in Cancer: From Mechanisms to Therapies Glutathione peroxidase 4‐dependent glutathione high‐consumption
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Glutathione peroxidase 4dependent glutathione highconsumption drives acquired platinum chemoresistance in lung cancerderived brain metastasis Liu 2021 Clinical and Translational Medicine Wiley Online Library Glutathione: Lights and Shadows in Cancer Patients PMC Frontiers Glutathione S conjugates as prodrugs to target drug resistant tumors Advances in platinum based cancer therapy: overcoming platinum resistance through rational combinatorial strategies PMC

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16, 21 Therefore, we have undertaken extensive studies to determine the potential for BSO to enhance the anti-myeloma activity of L-PAM at clinically achievable doses using in vitro (cell lines and fresh MM explants) and in vivo MM xenografts to determine if BSO+L-PAM warrants clinical trials in MM