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10.1016/j.vaccine.2012.10.083 Vaccine 115 LaliberteJ.CaiY.KennyT.ZhangY.RenK.RosenthalK.et al

Conclusion The gut microbiome plays a vital role in maintaining the astronauts health throughout the mission

This appears to involve a particular enzyme complex called mitochondrial complex I

Significant changes in body composition, such as increased lean muscle and decreased visceral fat, are typically achieved after 3 to 6 months of consistent therapy as part of a Hormone Optimization plan