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An approved drug that inhibits NADH:ubiquinone oxidoreductase is the biguanide metformin 41 , the first-line treatment in type II diabetes 41

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Group II (Intermittent Fasting Group): This set of animals (15 rats, 5 rats/cage) underwent an alternate-day fasting regimen in which they were given free access to food for 24 h and then disallowed for the next 24 h