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CYP450 Another family of enzymes involved in the metabolism of AA to eicosanoids, but also responsible for the metabolism of sterols, steroids, vitamin A, and vitamin D, are the enzymes from the cytochrome P450 (CYP450) family [131], which are also the most versatile class of enzymes metabolizing xenobiotics, including drugs, both in the liver and extrahepatically, including in the skin [131, 132]

EDTA Is a Better Anticoagulant than Heparin or Citrate for Delayed Blood Processing for Plasma DNA Analysis

Role of NRF2 and KEAP1 in the regulation of GSH abundance NRF2 is regarded as a major contributor to cell survival and redox balance and is regulated by KEAP1, an adapter protein of Cullin 3 (Cul3) containing E3 ubiquitin ligases

On one hand, glutamate can be directly converted to -KG by glutamate dehydrogenase (GLDH), which was involved in the tricarboxylic acid (TCA) cycle as a metabolite for cancer cell growth and proliferation