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Materials and methods Anti-mouse CD38 antibodies (Ab68 and Ab69) Ab68 and Ab69 antibodies UniAb clone ID337468 (Ab68) and UniAb clone ID337469 (Ab69) expressed on a silenced mouse IgG2a background are from Teneobio Inc (Newark, CA), that have been silenced to assure long half-lives, reduced immunogenicity, absence of immune effector functions, and without cytotoxic effect on CD38 positive cells

Cushing's syndrome: Update on signs, symptoms and biochemical screening

The cycling protocols commonly recommended are partly based on this theoretical concern, though actual tolerance development has not been documented

But it also means you need to continuously consume them to avoid becoming deficient