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Samarelli et al (2020) demonstrated that, whilst RABGAP1 is mostly cytosolic at steady state, it also co-localises with RAB11A-positive recycling endosomes and RAB5-positive early endosomes, but does not co-localise with lysosomal markers RAB7 and LAMP1

Accordingly, these findings underscore the need to investigate how the interplay between amino acid metabolism and byproduct accumulation contributes to the observed phenotypic drift and production instability

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81900624), the China Postdoctoral Science Foundation (No.2022M722901), the Key R&D and Promotion Special Projects of Henan Province (No