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La prctica deportiva de resistencia, especialmente en condiciones calurosas, puede generar microlesiones intestinales

10.1016/j.freeradbiomed.2018.11.016 17

Through injection of -syn preformed fibrils (PFFs) into the striatum of transgenic mice, researchers demonstrated the development of Lewy pathology, nigrostriatal degeneration, and importantly expanded our understanding of cell-to-cell transmission by describing the nature of spread in neuroanatomically connected regions: this provided the first evidence that synthetic -syn PFFs alone can induce the initiation and propagation of -syn pathology in vivo (Luk et al., 2012)