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The PubMed, Cochrane Library, OvidSP, Web of Science, China Science and Technology Journal Database, Chinese National Knowledge Infrastructure and China Wanfang Standards Database databases were systematically searched from the inception dates to October 1st, 2019, using the key wordsglutathione or GSH and Parkinson or Parkinson's disease or PD

Laboratory investigations comprised creatine phosphokinase, liver enzymes, and a comprehensive metabolic workup, including blood lactate, ammonia, plasma amino acids, acylcarnitine profile, urine organic acids, very-long-chain fatty acids, glucose, and cerebrospinal fluid neurotransmitters, according to standard clinical protocols

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Experimental literature often explores glutathiones relationship to cytokine signaling , cellular stress responses, and immune-cell functionparticularly in contexts where oxidative stress and inflammation intersect (metabolic strain, toxin exposure, high training loads, or aging-related oxidative burden)