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10.1146/annurev-physiol-042222-024535 Annu Rev Physiol

Genetic variations in enzymes involved in one carbon metabolism, such as the MTHFR gene, can also reduce methylation efficiency

If you're 35, metabolically healthy, training well, sleeping well, and just curious about peptides because you heard Joe Rogan talk about them, the honest answer is: your time and money are probably better spent elsewhere first