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That recognition matters

Structural verification (TEM): Transmission electron microscopy should confirm the presence of intact, closed vesicle structures displaying the characteristic "dark-light-dark" trilamellar membrane profile

With the recent broad recognition of click chemistry and bioorthogonal chemistry, we anticipate a surge in research in the years to come, driving further advancements in biocompatible techniques for peptide macrocyclisation and expanding the toolkit of chemical methods for protein and cellular ligation

Menzel T., Rahman Z., Calleja E., et al., Elevated Intracellular Level of Basic Fibroblast Growth Factor Correlates With Stage of Chronic Lymphocytic Leukemia and Is Associated With Resistance to Fludarabine, Blood 87 (1996): 10561063