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The nitric oxide/ascorbate cycle: how neurones may control their own oxygen supply

LMNA mutations induce a non-inflammatory fibrosis and a brown fat-like dystrophy of enlarged cervical adipose tissue

doi: 10.3389/fnmol.2024.1408159 Received 27 March 2024 Accepted 14 June 2024 Published 09 July 2024 Volume 17 - 2024 Edited by Eva Zerovnik, Institut Joef Stefan (IJS), Slovenia Reviewed by Jeffrey Liddell, The University of Melbourne, Australia Ali Yousefian-Jazi, Korea Institute of Science and Technology (KIST), Republic of Korea Updates Copyright 2024 Min, Sarlus and Harris

GBL1 is synthesized as an 85-kDa precursor that is C-terminally processed into a 64-66 kDa mature form and the released ~20-kDa proteolytic fragment was thought to be degraded (PMID: 10744681)