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Choline supplementation alleviates fluoride-induced testicular toxicity by restoring the NGF and MEK expression in mice

Moreover, high-dose L-carnitine supplementation completely prevented the reduction in mitochondrial function markers (Figures 5C, D), and ultimately attenuated cytotoxicity (Figure 5E) in lenvatinib-treated C2C12 myocytes

doi: 10.1590/S1519-9940210332020 55 von KnoblauchTJensenABMllingCKWAupperle-LellbachHGenerschE

It has crucial impacts on the growth and diseases of the abovementioned organisms ( 2.1 Iron accumulation Iron is crucial for various life activities of cells ( Figure 1 ) ( Figure 1 Excessive free iron leads to iron accumulation, which triggers nonenzymatic, iron-dependent Fenton chain reactions that directly produce excessive reactive oxygen species, thereby causing oxidative damage to cells ( Figure 1 )