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TB-4: cell migration Full-length thymosin beta-4 (43 amino acids) moves repair cells (fibroblasts) into position and helps coordinate their movement through tissue (G-actin sequestration). It biases healing toward functional tissue over rope-like scarring (Ac-SDKP anti-fibrotic signaling) and calms blood-vessel cells, which shows up as less redness. GLOW uses the full-length parent, not the shorter TB-500 fragment

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SIRT1 deacetylates SREBP-1c and ChREBP, suppressing the expression of their downstream lipogenic genes, ultimately inhibiting lipogenesis and mitigating MAFLD [28,29]