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In: New York: Oxford University Press

In addition to its established role in apoptosis, recent evidence has confirmed Taus involvement in regulating other RCD

Interestingly, DHODH and GPX4 constitute two primary defenses to detoxify lipid peroxidation in the mitochondria, and inhibiting one pathway can enforce cell more partial to the other one, whereas inactivation of both can lead to ferroptosis triggered by mitochondrial lipid peroxidation (Mao et al., 2021)