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Drug library screening identified several promising radioprotective compounds The glutathione and senescence assays were used to screen a library of FDA-approved drugs (Selleck Chemicals) at 100 M

Knock-out of IGF-1 in the liver alone results in relatively normal sized mice with a 75% reduction in circulating IGF-1 levels, suggesting that local IGF-1 may be more important for body growth than liver IGF-1 [18]