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Future studies should incorporate models with greater human relevance, including humanized mouse systems and patient-derived organoids, to more reliably evaluate drug exposure, toxicity and lactylation-dependent signaling

Single-cell gene expression quantification The raw sequencing data were processed using Cell Ranger (v5.0) provided by 10X Genomics with the default options

doi: 10.1016/j.tcb.2022.03.001

87,88 FMT transplant materials include liquid and capsule forms, with administration methods including upper gastrointestinal tract liquid injection, lower gastrointestinal tract liquid injection, and oral capsules