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Additionally, DF-Cur promoted the excretion of Cu 2+ and reduced its accumulation in vivo , alleviating the damage to nervous system (Wang M

[PubMed: 37209197] 20

( D ) Relative expression of CHAC1 in liver biopsies from MASLD/MASH

However, this approach faces several challenges, including the potential for the blood-brain barrier (BBB) to mask or dilute CNS-specific signals and the difficulty in distinguishing brain-derived markers from those originating systemically (87,88)