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Like HGH, Sermorelin benefits include decreased body fat reduction, increase in lean muscle, deeper sleep, improved recovery, increased sex drive, and improved cognition

RPMI-1640 medium, high-glucose DMEM were obtained from Thermo Fisher Scientific Inc

Monitoring Schedule Serum IGF-1 at baseline and at 8-12 weeks Fasting glucose at baseline and every 3-6 months (GH increases insulin resistance acutely) Thyroid panel at baseline (hypothyroidism blunts IGF-1 response) Blood pressure and fluid retention assessment at each visit The American Association of Clinical Endocrinology (AACE) recommends IGF-1 be kept within the age- and sex-adjusted reference range during any GH-stimulating therapy to minimize risk of adverse effects including fluid retention and glucose intolerance [9]

These are ongoing areas of laboratory exploration and remain investigational