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In the year 2000 more than four thousand out of approximately 12,500 Kiowa lived near the towns of Anadarko, Fort Cobb, and Carnegie, in Caddo and Kiowa counties, Oklahoma

Both were cleverly concealed, even after eight centuries

Moreover, we selected 5 mg/kg LicoA for the subsequent verification after the preliminary experiments, this dosage selection aligns with findings reported in a previous study ( Renal tubular epithelial cell (RTEC) injury and death are central to the pathogenesis and progression of CKD (Zhao et al., 2023)

This article was financially supported by National Institutes of Health Public Health Service grants R01 HL144790, R01 HL151493, R01 AI145813, R01 AI169687, R01 HL151769, and R01 HL159804 (OA)