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Similarly, a previous preclinical study of VE supplementation did not significantly alter plasma levels of the pro-fibrotic cytokine TGF-1 or the adipocytokine leptin compared to the cholesterol-fed control group

Chimploy K, Diaz GD, Li Q, Carter O, Dashwood WM, Mathews CK, Williams DE, Bailey GS, Dashwood RH (2009) E2F4 and ribonucleotide reductase mediate S-phase arrest in colon cancer cells treated with chlorophyllin

Methodological Confounds That Must Be Considered Before Comparing Cytokine Studies The biological mechanisms of cytokines make a consistent and stable circulating profile unlikely, which limits the ability of peripheral cytokines to provide insight into underlying pathophysiology in ME/CFS

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