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Phase IV - after the medicine has received regulatory approval, designed to evaluate the long-term effects

For people with type 2 diabetes, especially those with microvascular complications, boosting glutathione levels could help mitigate the harmful effects of oxidative stress and slow down the progression of complications

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+-More strikingly, the findings suggest that GPX4 plays a crucial role in preserving intestinal homeostasis by protecting against lipid peroxidation, as evidenced by the increased vulnerability of IEC Gpx4 mice to DSS-induced colonic inflammation relative to their wild-type counterparts (65)