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Since collagen is usually derived from animal protein sources, nutritionist-dietitian Samantha Morales states that those with allergies to fish, seafood, and egg or those on vegetarian and vegan diets can't take collagen supplements

However, according to Yang et al

We detected a parkin deficiency-associated increase in the ratio of reduced glutathione (GSH) to oxidized glutathione (GSSG) in murine brain, PRKN- linked human cortex and several cell models

We review current knowledge of skin copper/zinc superoxide dismutase including recent studies in an attempt to contribute to solving the question of its remaining unexplained functions