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Loss of the neurotransmitter dopamine, due to the degeneration of dopaminergic neurons in the midbrain underlies the pathophysiology of the motor dysfunction

Acknowledgements The authors would like to sincerely thank the following individuals and institutions who made vital contributions to this study: We thank Rhyad Al-issa from the Department of Biochemistry, College of Medicine, King Khalid University, for his technical support in the preparation of the electron microscopic slides

Ziebell and Morganti-Kossmann, 2010)

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