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Ayers M, Lunceford J, Nebozhyn M, Murphy E, Loboda A, Kaufman DR, et al

Nanotechnology-based carriers, receptor-targeted delivery platforms, intranasal nanoparticle systems, and extracellular vesicle-based formulations have demonstrated improved pharmacokinetics, controlled release, and enhanced CNS accumulation in preclinical studies, with several advanced platforms now progressing into early-phase clinical evaluation for AD and related neurodegenerative disorders