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Discovery of a potent and highly selective dipeptidyl peptidase IV and carbonic anhydrase inhibitor as antidiabesity agents based on repurposing and morphing of WB-4101

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Diabetes Obes

have revealed that GADD45 suppresses hepatic gluconeogenesis by stabilizing and activating forkhead box protein O1 (FoxO1), while GADD45 knockout increased expression of lipogenesis-related genes