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Med 22 , 298 (2022)

A COA can document a batch

In a high quality 28-day study in 34 women with mild to moderate constipation, taking 1.5 grams (g) of magnesium oxide per day significantly improved stool consistency, quality of life, and the time it took digested food to move through the colon, compared with a placebo ( Studies have also shown that magnesium citrate and mineral water containing magnesium sulfate helped treat constipation ( Keep in mind that magnesium sulfate may cause digestive side effects such as bloating and diarrhea

Since expression from T7-based plasmids can often lead to this type of severe insoluble accumulation, we decided to test an alternative expression plasmid, pMAZ360, that was previously shown to be optimized for E-clonal production 22