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We also note that we proposed for this measure to begin with the CY 2027 reporting period, not the CY 2026 reporting period as the commenter noted

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therefore, MAO-driven metabolism of substances such as dopamine, serotonin, norepinephrine, and tyramine normalizes only after new MAO is synthesized, and this process takes about 2 weeks to be complete after the MAOI has been washed out of the body