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Dieser kann als pathologischer Zustand definiert werden, in dem mehr freie Radikale vorhanden sind, als der menschliche Krper in der Lage ist, ihnen entgegenzuwirken

Cancer Genomics Proteomics 21, 305315

Beyond cell models, utilizing an organ-on-a-chip model, which is a microfluidic cell culture device that replicates the structure and function of a specific human organ or tissue, may allow researchers to study organ-level responses to drugs, phytonutrients, or synergistic combinations of nutrients in a controlled environment (111113)

Moreover, attention has been given to the mechanisms of action of low-molecular-weight antioxidants (vitamin C (ascorbate), vitamin E (alpha-tocopherol), carotenoids (e.g., -carotene, lycopene, lutein), flavonoids (e.g., quercetin, anthocyanins, epicatechin), and glutathione (GSH)), the activation of transcription factors such as Nrf2, and the protection against chronic diseases