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It is then possible that intake of these nutrients may re-establish an optimal natural balance for the Nrf2 pathway and mitigate COVID-19 severity (Bousquet et al., 2020)

For example, senescent cells upregulate BCL2 family proteins such as BCL-XL, BCL-W 24 or MCL-1 25 to prevent intrinsic apoptosis

In this review, we describe the central roles of mitochondria in oxidative stress, inflammation, and aging, especially mechanisms in diseases, and the current mainstream drugs targeting mitochondria