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Hampson et al

Matrix metalloproteinase-9 mediates hypoxia-induced vascular leakage in the brain via tight junction rearrangement

However, additional scientific evidence is required supporting this benefit

Non-canonical IGF-1R signaling We use the term non-canonical signaling to describe signal transduction pathways of IGF-1R that operate either independently or upstream of PI3K/AKTRas/MAPK routes