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As an alternative drug delivery route, topical medications have not shown promising results and need further evaluation in future trials

More preferably, the optically pure compound of formula (II) in the present invention is crystalline solid

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OCT6 ( SLC22A16 ) is mainly highly expressed in the testis and is a high-affinity carnitine transporter, which can also transport a variety of substrates (e.g., tetraethylammonium, spermidine and doxorubicin) [175]