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QC: methodology, formal analysis, writing-original draft

Three weeks after surgery, we assessed the learning capabilities and the short-term memory of three experimental groups using the conventional y-maze test: (i) streptozotocin-treated rats (BHT pre-treatment), (ii) streptozotocin-treated rats (no BHT pre-treatment), (iii) sham-operated rats (BHT pre-treatment but no streptozotocin administration)

Dose-dependent organ toxicity, long-term safety profiles, and potential interactions with medications commonly administered to AKI patients, such as antibiotics, vasopressors, and nephrotoxic agents, must be systematically evaluated