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Collectively, these results suggest that the HMO nanosystem is capable of generating ROS in situ within the cytoplasm and controllably releasing NO

Inhibition of nitric oxide synthesis potentiates apoptosis in the rabbit corpus luteum

Calcium ions also bind to troponin and alter its spatial conformation, permitting tropomyosin movement on the thin filament to expose the myosin-binding site on actin, resulting in actin-myosin interaction and contraction 44