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Although it is well-established that cigarette smoke predisposes individuals to pulmonary disease, mucus cell hyperplasia, decreased cilia, and decreased ciliary beat, animal models have not addressed the long-term effects of chronic cigarette smoke exposure on ciliated airway epithelium

The tobacco industry has been working to align itself with African American advocacy groups in a bid to resist further regulation

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According to Hukkanen, J., Jacob, P.s 2005 study, Metabolism and disposition kinetics of nicotine., the pharmacokinetic properties of nicotine, or the way it is processed by the body, contribute to its addictiveness