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Acknowledgements We would like to acknowledge the assistance of the Penn State Department of Pharmacy Services, including Lisa Braccini-Barletta, Richard Sargent, and Jennifer Sauter, and the George Washington University Investigational Drug Service with the research cigarette inventory

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Cigarette burns, for example, are characteristically third-degree burns with a diameter of 7 to 10mm

While flavors can vary widely, there are some baseline categories that appear frequently: Spicy Black pepper, red pepper, cinnamon Sweet Caramel, molasses, dried fruit Creamy Butter, vanilla, cashew Robust Espresso, cocoa, dark chocolate Woody Cedar, oak, sandalwood Earthy Soil, leather, mushroom Funky Barnyard, fermented notes (often prized in aged cigars) Flavors also evolve throughout the smoke